Metabolic
MOTS-c
$55.00 CAD
All prices shown in Canadian Dollars (CAD) · 🍁 Ships Canada-wide
A mitochondrial-derived peptide studied for boosting cellular energy, improving insulin sensitivity, and enhancing metabolic function. Research suggests benefits for fat loss, exercise performance, longevity, and overall vitality.
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Specifications
- Purity
- ≥99%
- Quantity
- 10mg
- Storage
- Lyophilized: -20°C. Reconstituted: 2-8°C
- Research Use
- Laboratory research only. Not for human use.
1. Overview
Full name
Mitochondrial ORF of the 12S rRNA-c
Category
Mitochondrial-Derived Peptide / Metabolic
Abbreviations
Summary
A 16-amino-acid peptide encoded within mitochondrial DNA. Acts as a metabolic regulator and exercise-mimetic, improving insulin sensitivity and cellular energy efficiency.
2. What It Does
Primary functions
- Improves insulin sensitivity and glucose uptake
- Enhances mitochondrial efficiency
- Supports fat oxidation
- Mimics exercise-induced adaptations
Secondary effects
- Reduces age-related metabolic decline
- Improves endurance
- Modulates inflammatory tone
Biological pathways
- AMPK activation
- Folate-methionine-AICAR cycle
- GLUT4 translocation in skeletal muscle
Mechanisms of action
- Activates AMPK to shift metabolism toward energy production
- Increases glucose uptake into skeletal muscle
- Improves mitochondrial biogenesis
3. How It Works
MOTS-c is released by mitochondria and acts as a hormone-like metabolic signal. It activates AMPK, the master regulator of cellular energy, prompting cells to burn glucose and fat more efficiently.
It enhances GLUT4 expression and translocation in muscle, improving insulin sensitivity even in metabolically compromised states, and supports mitochondrial biogenesis associated with healthy aging.
4. Benefits
Insulin sensitivity
Improved glucose disposal.
Fat oxidation
Enhanced lipid metabolism.
Endurance
Increased exercise capacity in research models.
Longevity
Counteracts age-related metabolic decline.
Energy
Improved cellular ATP production.
Vitality
Exercise-mimetic systemic effects.
5. Why People Use It
Common goals
- Metabolic health
- Endurance
- Longevity
- Fat loss
Typical use cases
- Metabolic syndrome research
- Aging studies
- Exercise physiology
Popular applications
- Mitochondrial health research
- Insulin sensitivity studies
Who uses it
- Longevity researchers
- Metabolic scientists
- Performance labs
